Synthesis, characterization, in vitro tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibition studies and computational evaluation of novel thiazole derivatives

Synthesis, characterization, in vitro tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP) inhibition studies and computational evaluation of novel thiazole derivatives

alkaline phosphatase (AP) is a homodimeric enzyme class that has the ability dephosphorylation physiological. AP catalyzes the hydrolysis of monoesters into phosphoric acid which in turn catalyzes transfosforilasi. Thiazoles are nitrogen and sulfur-containing aromatic heterocycles AP regarded as effective inhibitors.

In this context, research papers currently presenting a successful synthesis, spectroscopic characterization and in vitro alkaline phosphatase inhibition potential new thiazole derivatives. Structure activity relationship and molecular docking studies conducted to determine the binding mode of the compound screened by the target site tissue non-specific alkaline phosphatase (h-TNAP) and intestinal alkaline phosphatase (h-IAP). 5e compound was found to be a potent inhibitor of h-TNAP with IC50 of 0.17 ± 0.01 pM.

In addition, the compounds 5a and 5i are found to be very selective about the h-TNAP with IC50 values ​​of 0.25 ± 0.01 and 0.21 ± 0.02 pM pM, respectively. In the case of h-IAP inhibitor compound 5f is the most potent with IC50 value of 1.33 ± 0.10 pM. The most active compound is a molecular docking studies on the resort-TNAP h and h-IAP binding interactions to explore the possibility of enzyme-ligand complex. performed molecular dynamics simulations to investigate the overall stability of the protein in the apo and holo country.

Breast cancer is often characterized by calcification in mammography. Mechanisms for calcifications in breast cancer is not fully known. Understanding these mechanisms will improve diagnostic accuracy. Here, we show that calcification occurs and that alkaline phosphatase enzyme activity increased MDA-MB-231 cells were cultured using a cocktail containing osteogenic media.

Transcript microarray analysis showed that PI3K-Akt signaling were significantly involved, with the recruitment of placental alkaline phosphatase. Calcification and alkaline phosphatase enzyme activity was suppressed by placental alkaline phosphatase silencing using small interfering RNA. Inhibition of PI3K-Akt signaling pathway is pressed phospho-c-Jun and placental alkaline phosphatase and resulted in the absence of calcification.

CEVO oxidase catalysis combines 4-mimetic with hexametaphosphate ion induced aggregation for sensing electrostatic photometry alkaline phosphatase activity

In this study, a new alkaline phosphatase (ALP) activity colorimetric assay proposed by integrating the catalytic characteristics oxidase-mimicking nanoparticles CeVO4 with hexametaphosphate ion (HMPi) mediated electrostatic aggregation.

The CeVO4 nanoparticles showed excellent catalytic ability oxidase-mimetic to promote 3,3 ’, 5,5′-tetramethylbenzidine (TMB) oxidation TMBox, offers significant changes from colorless to blue. After a small amount HMPi added, a strong electrostatic interaction between the negatively charged species HMPi and positively charged TMBox leads aggregation of the last product, produce eggplant HMPi-TMBox clot.

After the clot is filtered out, it turns out the reaction solution becomes almost colorless. When the ALP used to hydrolyze HMPi species in advance, electrostatic aggregation process is highly controllable, so that it retains the blue color CeVO4 catalyzed TMB solution.

Alkaline Phosphatase antibody

70R-13468 100 ul
EUR 548.4
Description: Affinity purified Rabbit polyclonal Alkaline Phosphatase antibody

Alkaline Phosphatase Antibody

48608-100ul 100ul
EUR 399.6

Alkaline Phosphatase Antibody

48608-50ul 50ul
EUR 286.8

Alkaline Phosphatase Antibody

F40345-0.4ML 0.4 ml
EUR 322.15
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Alkaline Phosphatase Antibody

F44128-0.4ML 0.4 ml
EUR 322.15
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Alkaline Phosphatase Antibody

F44129-0.4ML 0.4 ml
EUR 322.15
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Alkaline Phosphatase Antibody

E80806-3 100μl
EUR 225
Description: Available in various conjugation types.

Alkaline Phosphatase Antibody

DF4722-100ul 100ul
EUR 280

Alkaline Phosphatase Antibody

DF4722-200ul 200ul
EUR 350

Alkaline Phosphatase Antibody

DF6225-100ul 100ul
EUR 280

Alkaline Phosphatase Antibody

DF6225-200ul 200ul
EUR 350

Alkaline Phosphatase Antibody

BF0179-100ul 100ul
EUR 350

Alkaline Phosphatase Antibody

BF0179-200ul 200ul
EUR 450

Alkaline Phosphatase Antibody

BF0179-50ul 50ul
EUR 250

Alkaline Phosphatase Antibody

BF0179 100ul
EUR 350
Description: Human

Alkaline Phosphatase Antibody

DF4722 100ul
EUR 280
Description: Human,Mouse,Rat

Alkaline Phosphatase Antibody

DF6225 100ul
EUR 280
Description: Human,Mouse,Rat

Alkaline Phosphatase (AP) Antibody

abx020685-1mg 1 mg
EUR 526.8

Human Alkaline Phosphatase Antibody

32918-05111 150 ug
EUR 313.2

Alkaline Phosphatase Antibody (liver)

F44128-0.08ML 0.08 ml
EUR 140.25
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Alkaline Phosphatase Antibody (liver)

F44129-0.08ML 0.08 ml
EUR 140.25
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.

Alkaline Phosphatase (ALP) Antibody

20-abx175316
  • EUR 1412.40
  • EUR 693.60
  • 1 mg
  • 200 ug

Alkaline Phosphatase (ALP) Antibody

20-abx175317
  • EUR 1496.40
  • EUR 710.40
  • 1 mg
  • 200 ug

Alkaline Phosphatase (ALP) Antibody

20-abx121265
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

GST Antibody (Alkaline Phosphatase)

abx448867-100ug 100 ug
EUR 727.2

CBP Antibody (Alkaline Phosphatase)

abx449065-100ug 100 ug
EUR 727.2

CBP Antibody (Alkaline Phosphatase)

abx449083-100ug 100 ug
EUR 727.2

BAD Antibody (Alkaline Phosphatase)

abx449461-100ug 100 ug
EUR 727.2

BAD Antibody (Alkaline Phosphatase)

abx449479-100ug 100 ug
EUR 727.2

Alkaline Phosphatase(V17.1) Antibody

BNCA0141-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(V17.1), APC conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC800141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF680 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC800141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF680 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC810141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC810141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC940141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC940141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC700141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF770 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC700141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF770 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC880141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC880141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase (ALP) Antibody

abx038456-100ug 100 ug
EUR 469.2

Alkaline Phosphatase(V17.1) Antibody

BNC430141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF543 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC430141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF543 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC400141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF640R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC400141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF640R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC050141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC050141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCAP0141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCAP0141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCB0141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCB0141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCR0141-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(V17.1), RPE conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNUB0141-100 100uL
EUR 250.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Concentration: 0.2mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNUB0141-500 500uL
EUR 549.6
Description: Primary antibody against Alkaline Phosphatase(V17.1), Concentration: 0.2mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCP0141-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(V17.1), PerCP conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNUM0141-50 50uL
EUR 474
Description: Primary antibody against Alkaline Phosphatase(V17.1), 1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCH0141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNCH0141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC040141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC040141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC550141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF555 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC550141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF555 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC610141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF660R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC610141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF660R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC680141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF568 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC680141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF568 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC470141-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF647 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(V17.1) Antibody

BNC470141-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(V17.1), CF647 conjugate, Concentration: 0.1mg/mL

Placental alkaline phosphatase Antibody

abx139037-01mg 0.1 mg
EUR 393.6

Placental alkaline phosphatase Antibody

49615-100ul 100ul
EUR 399.6

Placental alkaline phosphatase Antibody

49615-50ul 50ul
EUR 286.8

Alkaline phosphatase Antibody (placental)

F54020-0.1ML 0.1 ml
EUR 322.15

Alkaline phosphatase Antibody (placental)

F40345-0.08ML 0.08 ml
EUR 140.25
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Alkaline Phosphatase Antibody (placental)

F43061-0.08ML 0.08 ml
EUR 140.25
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). Placental ALP is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form.

Alkaline Phosphatase Antibody (placental)

F44307-0.08ML 0.08 ml
EUR 140.25
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Placental Alkaline Phosphatase Antibody

F44307-0.4ML 0.4 ml
EUR 322.15
Description: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.

Alkaline phosphatase Antibody (placental)

R32610 100 ug
EUR 356.15
Description: Alkaline phosphatase, placental type also known as placental alkaline phosphatase (PLAP) is an allosteric enzyme that in humans is encoded by the ALPP gene. The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

Kir4.1 Antibody (Alkaline Phosphatase)

abx445829-100ug 100 ug
EUR 693.6

KDEL Antibody (Alkaline Phosphatase)

abx448669-100ug 100 ug
EUR 727.2

KDEL Antibody (Alkaline Phosphatase)

abx448687-100ug 100 ug
EUR 727.2

KDEL Antibody (Alkaline Phosphatase)

abx448705-100ug 100 ug
EUR 727.2

MEK1 Antibody (Alkaline Phosphatase)

abx449569-100ug 100 ug
EUR 727.2

LRP1 Antibody (Alkaline Phosphatase)

abx449659-100ug 100 ug
EUR 727.2

LRP1 Antibody (Alkaline Phosphatase)

abx449677-100ug 100 ug
EUR 727.2

DKK1 Antibody (Alkaline Phosphatase)

abx449713-100ug 100 ug
EUR 727.2

Alkaline Phosphatase (ALPP) Antibody

abx019006-100ug 100 ug
EUR 410.4

Alkaline Phosphatase (ALPL) Antibody

abx019007-100ug 100 ug
EUR 410.4

Alkaline Phosphatase (ALPI) Antibody

abx028323-400ul 400 ul
EUR 627.6

Alkaline Phosphatase (ALPI) Antibody

abx028323-80l 80 µl
EUR 343.2

Alkaline Phosphatase (ALPI) Antibody

20-abx101821
  • EUR 393.60
  • EUR 159.60
  • EUR 1062.00
  • EUR 543.60
  • EUR 326.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Alkaline Phosphatase (ALPI) Antibody

20-abx101822
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Alkaline Phosphatase-Anti-Alkaline Phosphatase Complex (APAAP) Antibody

abx415801-1ml 1 ml
EUR 610.8

GRP94 Antibody (Alkaline Phosphatase)

abx448723-100ug 100 ug
EUR 727.2

Tbj51 Antibody (Alkaline Phosphatase)

abx448975-100ug 100 ug
EUR 727.2

SMAD3 Antibody (Alkaline Phosphatase)

abx449119-100ug 100 ug
EUR 727.2

SFRP1 Antibody (Alkaline Phosphatase)

abx449317-100ug 100 ug
EUR 727.2

PDGFB Antibody (Alkaline Phosphatase)

abx449407-100ug 100 ug
EUR 727.2

4EBP1 Antibody (Alkaline Phosphatase)

abx449605-100ug 100 ug
EUR 727.2

SFRP2 Antibody (Alkaline Phosphatase)

abx449695-100ug 100 ug
EUR 727.2

FOXO1 Antibody (Alkaline Phosphatase)

abx449767-100ug 100 ug
EUR 727.2

PDGFB Antibody (Alkaline Phosphatase)

abx449803-100ug 100 ug
EUR 727.2

Rabbit polyclonal antibody to alkaline phosphatase(intestinal) (alkaline phosphatase, intestinal)

TA308737 100 µl Ask for price

CDKN2A Antibody (Alkaline Phosphatase)

abx449497-100ug 100 ug
EUR 727.2

RICTOR Antibody (Alkaline Phosphatase)

abx449893-100ug 100 ug
EUR 727.2

TbHsp70 Antibody (Alkaline Phosphatase)

abx448993-100ug 100 ug
EUR 727.2

Palladin Antibody (Alkaline Phosphatase)

abx449857-100ug 100 ug
EUR 727.2

Alkaline Phosphatase(ALP/597) Antibody

BNCA0597-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(ALP/597), APC conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC800597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC800597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC810597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC810597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF680R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC940597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC940597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF594 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC700597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF770 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC700597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF770 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC880597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC880597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF488A conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC400597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF640R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC400597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF640R conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC050597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC050597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405M conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCB0597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCB0597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Biotin conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCAP0597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCAP0597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCR0597-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(ALP/597), RPE conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCP0597-250 250uL
EUR 459.6
Description: Primary antibody against Alkaline Phosphatase(ALP/597), PerCP conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNUM0597-50 50uL
EUR 474
Description: Primary antibody against Alkaline Phosphatase(ALP/597), 1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCH0597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNCH0597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNUB0597-100 100uL
EUR 250.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Concentration: 0.2mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNUB0597-500 500uL
EUR 549.6
Description: Primary antibody against Alkaline Phosphatase(ALP/597), Concentration: 0.2mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC040597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC040597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF405S conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC550597-100 100uL
EUR 238.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF555 conjugate, Concentration: 0.1mg/mL

Alkaline Phosphatase(ALP/597) Antibody

BNC550597-500 500uL
EUR 652.8
Description: Primary antibody against Alkaline Phosphatase(ALP/597), CF555 conjugate, Concentration: 0.1mg/mL

According to the new sensing strategy, analysis of a highly selective and sensitive ALP activity is realized, providing a wide detection range 1-210 U / L and a detection limit of 0.68 U / L. accurate measurement of ALP activity in serum matrix also clinically validated, demonstrate the practicality assay proposed in the practical application.