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Decrease in serum alkaline phosphatase and prognostic relevance in adult cardiopulmonary bypass
Objective: Cardiopulmonary bypass (CPB) induces an inflammatory response, which can cause loss of alkaline phosphatase (AP) consumed in the process of extracellular nucleotides dephosphorylating disadvantage in this proinflammatory state. It has been reported that the rate of postoperative low AP correlated with increased support needs post surgery and organ dysfunction after pediatric cardiac surgery. However, little is known about the development of perioperative and clinical relevance of depletion AP in adults undergoing CPB.
Methods: A total of 183 patients with left ventricular ejection fraction ≤50% preoperatively underwent mitral valve surgery ± concurrent procedure related in the Department of Cardiac Surgery, Medical University of Vienna, between 2013 and 2016 were included in this retrospective analysis. AP serum measurements at baseline and at days 1-15 post surgery were collected. AP absolute and relative reduction in postoperative day 1 of baseline parameters correlated with perioperative and postoperative early. Receiver operating characteristics used to determine predictors fit and cut-off for postoperative outcome variables.
Results: The operating characteristics Receiver showed a decrease of> 50% of the base AP to predict in-hospital mortality [area under the curve (AUC) 0.807], prolonged intensive care unit stay (> 72 hours, AUC 0.707), mechanical ventilation prolonged (> 24 hours, AUC 0.712) and need for dialysis-related operasi- (AUC 0.736). Patients with perioperative decrease in circulating AP to levels below 50% of the base has significantly decreased survival. Patients with high loss of perioperative AP AP preoperative levels of higher (P <0.001), longer duration of CPB (P <0.001) and a higher incidence of lung artificial support (P <0.001).
Conclusion: Increased perioperative AP loss associated with early adverse outcomes. prospective trial is needed to determine whether this effect can be neutralized by AP perioperative supplementation.
Difference Serum Alkaline Phosphatase Levels in Infants with spontaneous intestinal perforation compared Necrotizing enterocolitis with perforation
Introduction: Data laboratory markers spontaneous intestinal perforation (SIP) and necrotizing enterocolitis (NEC) remains sparse.
Objective: To compare serum levels of alkaline phosphatase in infants with intestinal perforation secondary to SIP vs NEC surgery, and then investigate the possible role of serum alkaline phosphatase to distinguish infants with this condition.
Methods: A retrospective case-control study of infants admitted with bowel perforation from 2005 to 2015. Demographics and Data prenatal, postnatal exposure, and clinical, laboratory, and radiographic findings were drawn from inpatient medical records and analyzed using regression analysis.
p38 Antibody |
48644-100ul |
SAB |
100ul |
EUR 399.6 |
p38 Antibody |
48644-50ul |
SAB |
50ul |
EUR 286.8 |
p38 Antibody |
35478-100ul |
SAB |
100ul |
EUR 468 |
p38 Antibody |
20-abx133223 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
p38 Antibody |
20-abx141038 |
Abbexa |
-
EUR 427.20
-
EUR 644.40
-
EUR 260.40
|
|
|
p38 Antibody |
20-abx007541 |
Abbexa |
-
EUR 360.00
-
EUR 526.80
-
EUR 226.80
|
|
|
p38 Antibody |
abx236076-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
p38 protein |
E20-80078 |
EnoGene |
20ug |
EUR 489.6 |
p38 protein |
E20-80079 |
EnoGene |
20ug |
EUR 489.6 |
anti-p38 |
YF-PA11120 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to p38 |
anti-p38 |
YF-PA11121 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to p38 |
anti-p38 |
YF-PA23519 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to p38 |
anti-p38 |
YF-PA23520 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to p38 |
anti-p38 |
YF-PA23521 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to p38 |
PPQ-102 |
B3504-10 |
ApexBio |
10 mg |
EUR 290.4 |
PPQ-102 |
B3504-5 |
ApexBio |
5 mg |
EUR 181.2 |
PPQ-102 |
B3504-50 |
ApexBio |
50 mg |
EUR 1035.6 |
PM 102 |
B5517-1 |
ApexBio |
1 mg |
EUR 721.2 |
MM-102 |
B1582-2 |
ApexBio |
2 mg |
EUR 153.6 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
MM-102 |
B1582-20 |
ApexBio |
20 mg |
EUR 711.6 |
Description: MM-102 is an antagonist of MLL1 with IC50 value of 2.4nM [1].Mixed lineage leukemia 1 (MLL1) is a histone H3 lysine 4 (H3K4) methyltransferase. |
5(6)-FAM [5-(and-6)-Carboxyfluorescein] *CAS 72088-94-9* |
102 |
AAT Bioquest |
25 g |
EUR 1051.2 |
|
SB-203580 p38 MAPK(p38 MAP kinase) Inhibitor |
E1B1863 |
EnoGene |
1mg |
EUR 193.2 |
p38 Polyclonal Antibody |
ABP53838-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
ABP53838-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
ABP53838-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180 |
p38 Polyclonal Antibody |
ABP53839-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
ABP53839-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
ABP53839-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IF, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y182 |
p38 Polyclonal Antibody |
ABP57354-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
p38 Polyclonal Antibody |
ABP57354-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
p38 Polyclonal Antibody |
ABP57354-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat, Chicken. This p38 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human p38 |
Anti-p38 alpha |
DB-1039 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 beta |
DB-1040 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 gamma |
DB-1041 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 delta |
DB-1042 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 alpha |
DB1039 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 beta |
DB1040 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 gamma |
DB1041 |
DB Biotech |
100 tests |
EUR 568.8 |
Anti-p38 delta |
DB1042 |
DB Biotech |
100 tests |
EUR 568.8 |
AIMP2/p38 Antibody |
DF12048 |
Affbiotech |
200ul |
EUR 420 |
anti- p38 antibody |
FNab06076 |
FN Test |
100µg |
EUR 606.3 |
|
Description: Antibody raised against p38 |
p38 Polyclonal Antibody |
ES3111-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
ES3111-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
ES3112-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
ES3112-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
ES8347-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
p38 Polyclonal Antibody |
ES8347-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat/Chicken. This antibody is tested and validated for WB, ELISA, WB, ELISA |
p38 Polyclonal Antibody |
ES4837-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
ES4837-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
p38 Polyclonal Antibody |
ES4838-100ul |
ELK Biotech |
100ul |
EUR 334.8 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
p38 Polyclonal Antibody |
ES4838-50ul |
ELK Biotech |
50ul |
EUR 248.4 |
Description: A Rabbit Polyclonal antibody against p38 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
P38 MAPK antibody |
70R-34325 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
70R-34327 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal P38 MAPK antibody |
p38 MAPK antibody |
70R-33398 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal p38 MAPK antibody |
p38 MAPK antibody |
70R-33400 |
Fitzgerald |
100 ug |
EUR 392.4 |
Description: Rabbit polyclonal p38 MAPK antibody |
p38 MAPK Antibody |
49379-100ul |
SAB |
100ul |
EUR 399.6 |
p38 MAPK Antibody |
49379-50ul |
SAB |
50ul |
EUR 286.8 |
P38 delta protein |
30R-2868 |
Fitzgerald |
5 ug |
EUR 603.6 |
Description: Purified recombinant Human P38 delta protein |
p38 alpha protein |
30R-2870 |
Fitzgerald |
5 ug |
EUR 603.6 |
Description: Purified recombinant Human p38 alpha protein |
p38 beta protein |
30R-2875 |
Fitzgerald |
5 ug |
EUR 603.6 |
Description: Purified recombinant Human p38 beta protein |
p38 MAPK antibody |
20R-2950 |
Fitzgerald |
100 ul |
EUR 471.6 |
Description: Rabbit polyclonal p38 MAPK antibody |
p38 Polyclonal Antibody |
41305-100ul |
SAB |
100ul |
EUR 302.4 |
p38 Polyclonal Antibody |
41305-50ul |
SAB |
50ul |
EUR 224.4 |
p38 Polyclonal Antibody |
41306-100ul |
SAB |
100ul |
EUR 302.4 |
p38 Polyclonal Antibody |
41306-50ul |
SAB |
50ul |
EUR 224.4 |
p38 MAPK antibody |
10R-8422 |
Fitzgerald |
100 ul |
EUR 471.6 |
Description: Mouse monoclonal p38 MAPK antibody |
p38 MAPK antibody |
20R-1572 |
Fitzgerald |
100 ug |
EUR 846 |
Description: Rabbit polyclonal p38 MAPK antibody |
P38 MAPK antibody |
20R-2087 |
Fitzgerald |
50 ug |
EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
20R-2088 |
Fitzgerald |
50 ug |
EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
P38 MAPK antibody |
20R-2403 |
Fitzgerald |
50 ug |
EUR 337.2 |
Description: Rabbit polyclonal P38 MAPK antibody |
p38 Blocking Peptide |
20-abx161932 |
Abbexa |
|
|
|
p38 (pY323) Antibody |
20-abx133058 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
p38 (pY182) Antibody |
20-abx134951 |
Abbexa |
-
EUR 460.80
-
EUR 727.20
-
EUR 276.00
|
|
|
p38 MAPK Antibody |
20-abx012798 |
Abbexa |
-
EUR 376.80
-
EUR 117.60
-
EUR 477.60
-
EUR 594.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
p38 MAPK Antibody |
20-abx012875 |
Abbexa |
-
EUR 376.80
-
EUR 117.60
-
EUR 477.60
-
EUR 594.00
|
- 100 ug
- 10 ug
- 200 ug
- 300 µg
|
|
p38 (pT180) Antibody |
20-abx009863 |
Abbexa |
-
EUR 376.80
-
EUR 560.40
-
EUR 243.60
|
|
|
p38 Polyclonal Antibody |
ABP52112-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
ABP52112-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
ABP52112-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of T180/Y182 |
p38 Polyclonal Antibody |
ABP52113-003ml |
Abbkine |
0.03ml |
EUR 189.6 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Polyclonal Antibody |
ABP52113-01ml |
Abbkine |
0.1ml |
EUR 346.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Polyclonal Antibody |
ABP52113-02ml |
Abbkine |
0.2ml |
EUR 496.8 |
|
Description: A polyclonal antibody for detection of p38 from Human, Mouse, Rat. This p38 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human p38 around the non-phosphorylation site of Y323 |
p38 Blocking Peptide |
20-abx061736 |
Abbexa |
|
|
|
p38 Blocking Peptide |
20-abx062080 |
Abbexa |
|
|
|
p38 MAPK Antibody |
abx236077-100ug |
Abbexa |
100 ug |
EUR 577.2 |
|
Anti-p38 Antibody |
A00176 |
BosterBio |
100ul |
EUR 476.4 |
Description: Rabbit Polyclonal Antibody for p38 Antibody (MAPK14) detection.tested for WB in Human, Mouse, Rat. |
anti-p38 MAPK |
LF-PA0160 |
Abfrontier |
100 ul |
EUR 400.8 |
Description: Rabbit polyclonal to p38 MAPK |
p38 alpha-MAPK14 |
RA15053 |
Neuromics |
100 ug |
EUR 631.2 |
Anti-p38 antibody |
STJ94876 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-p38 antibody |
STJ94877 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-p38 antibody |
STJ94878 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: p38 is a protein encoded by the MAPK14 gene which is approximately 41,2 kDa. p38 is localised to the cytoplasm and nucleus. It is involved in activated TLR4 signalling, the IL-2 pathway, toll-like receptor signalling pathways, the VEGF signalling pathway and 4-1BB pathway. This protein falls under the MAP kinase family. It acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. p38 is expressed in the brain, heart, placenta, pancreas and skeletal muscle. Mutations in the MAPK14 gene may result in patellar tendinitis and lumbosacral lipoma. STJ94878 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p38 protein. |
Anti-p38 antibody |
STJ94879 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-p38 antibody |
STJ97615 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Rabbit polyclonal to p38. |
Anti-P38 antibody |
STJ98898 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to P38. |
Anti-P38 antibody |
STJ98899 |
St John's Laboratory |
200 µl |
EUR 236.4 |
Description: Mouse monoclonal to P38. |
anti-Crk p38 |
YF-PA11088 |
Abfrontier |
50 ul |
EUR 435.6 |
Description: Mouse polyclonal to Crk p38 |
anti-Crk p38 |
YF-PA11089 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to Crk p38 |
anti-Crk p38 |
YF-PA11090 |
Abfrontier |
100 ug |
EUR 483.6 |
Description: Rabbit polyclonal to Crk p38 |
anti-Crk p38 |
YF-PA23509 |
Abfrontier |
50 ul |
EUR 400.8 |
Description: Mouse polyclonal to Crk p38 |
anti-AIMP2/p38 |
YF-PA15507 |
Abfrontier |
50 ug |
EUR 435.6 |
Description: Mouse polyclonal to AIMP2/p38 |
Anti-p38 (3D5) |
YF-MA12551 |
Abfrontier |
200 ul |
EUR 435.6 |
Description: Mouse monoclonal to p38 |
Anti-p38 (1C9) |
YF-MA12552 |
Abfrontier |
100 ug |
EUR 435.6 |
Description: Mouse monoclonal to p38 |
p38 beta, Active |
7763-100 |
Biovision |
each |
EUR 5214 |
p38 beta, Active |
7763-5 |
Biovision |
each |
EUR 444 |
Mouse MAPK P38(P38 Mitogen-activated Protein Kinase) ELISA Kit |
EM1199 |
FN Test |
96T |
EUR 628.92 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.75 ng/ml |
Mouse P38 Mitogen-activated Protein Kinase (MAPK P38) CLIA Kit |
abx197397-96tests |
Abbexa |
96 tests |
EUR 990 |
|
p38 MAPK Rabbit pAb |
A8038-100ul |
Abclonal |
100 ul |
EUR 369.6 |
Results: Of the 114 infants included outborn, 48 babies have SIP (cases) and 66 have NEC (control). Upon entry of the hospital refers, serum alkaline phosphatase levels were significantly higher in infants with SIP, ie, the median value of versus236 782 U / L in patients with NEC (p <0.0001), with an adjusted odds ratio (OR) of 4.3 (p <0.05) when the level is> 500 U / L in a multivariate regression model. Infants with gestational age SIP has significantly younger, presented earlier in life, especially with pneumoperitoneum, and have a greater exposure to steroids and indomethacin compared infants with NEC. alkaline phosphatase levels decreased rapidly in infants with the following SIP entry.
Conclusion: A temporary increase in serum alkaline phosphatase levels were independently associated with SIP when compared to the NEC. Studies confirm the role of alkaline phosphatase in the diagnosis of the necessary SIP and has clinical implications and potential prognostic significance.